Allergy: Solving The Mystery Of IgE

Immunoglobulin E (IgE) is the main actor in the drama of allergy. The biological role of IgE in the immune response of an organism and the lack of control leading to allergy is the research topic of Gernot Achatz, Molekular Biology, University of Salzburg. At the 2nd European Congress of Immunology ECI 2009 held in Berlin the scientist presents new data revealing the evolution of IgE. Allergic diseases have risen dramatically during the last...

Food-energy Cellular Connection Revealed: Metabolic Master Switch Sets Biological Clock In...

Our body's activity levels fall and rise to the beat of our internal drums—the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas the master clock in the brain is set by light, the pacemakers in peripheral organs are set by food availability. The underlying molecular mechanism was...

Changing Our Clocks: New Research Explores How Our Bodies Keep Time

Our alarm clocks may spring forward on March 9, but our biological clocks may take longer to adjust. That’s because our internal clocks are so tightly wound to many physiological and behavioral processes. Researchers have learned that circadian rhythms—the 24-hour cycles that keep our bodies on time—are involved in sleep, weight gain, mood disorders, and a variety of diseases. Now, they’ve made remarkable strides in identifying...

Many Hospitalized With Swine Flu Had Been Healthy

While the majority of people hospitalized with the H1N1 swine flu have chronic medical conditions, many were healthy before coming down with the disease, a U.S. health official said Tuesday. More than half of hospitalized adults had conditions such as asthma, chronic lung diseases, heart disease or immune system disorders, Dr. Anne Schuchat, director of the U.S. Centers for Disease Control and Prevention's National Center for Immunization and Respiratory Diseases, said during...

Getting To The Core Of H1N1 Flu Deaths

Fatalities show lungs are overwhelmed; antiviral drugs, ventilation to replace lost oxygen can rescue patients Lung inflammation and respiratory failure are largely responsible for the fatal cases of H1N1 (swine) flu seen so far, three new studies show. The findings also confirm observations that the influenza hits young adults the hardest but can be fought off in many cases with the use of...

Signs Of Macular Degeneration May Predict Heart Disease

A large study found strong evidence that older people who have age-related macular degeneration (AMD) are at increased risk for coronary heart disease (CHD), although not for stroke. This result adds to mounting evidence that AMD and cardiovascular disease may share some risk factors–smoking, high blood pressure, inflammatory indicators such as...

Most H1N1 Patients With Respiratory Failure Treated With Oxygenating System Survive...

Despite the severity of disease and the intensity of treatment, most patients in Australia and New Zealand who experienced respiratory failure as a result of 2009 influenza A(H1N1) and were treated with a system that adds oxygen to the patient's blood survived the disease, according to a new study. The influenza A(H1N1) pandemic affected Australia and New Zealand during the 2009 southern hemisphere winter, causing an epidemic of...

Circadian Clockwork Takes Unexpected Turns

One group of neurons follow a different pattern than others that guide the brain’s master clock. On the television show “24” a silent countdown usually means a character has died. But for some cells in the brain’s time-keeping center, silent running is part of life. Cells in the suprachiasmatic nuclei, a tiny group of neurons in the hypothalamus, serve as a master clock to regulate the body’s circadian rhythms — daily fluctuations in hormone release, body temperature, blood pressure and other processes...

A Cure For Jet Lag? Scientists Identify Brain Cell Which Keeps...

The discovery of the brain cell which determines our sleep patterns could pave the way for the introduction of a pill to beat jetlag. A pill that cures jet lag is a step closer today, after scientists discovered how signals from the brain control our biological clocks. Tests on mice suggested the human body clock - controlled by a region of the brain called the suprachiasmatic nuclei...

Flu: Grim stats

A diagnosis of cancer, diabetes — even cirrhosis or Parkinson’s disease — will send shivers down the spines of most people. But flu? We tend to view it as little more than an occasional feverish nuisance that sends us to bed with joint pain, congestion and nausea (or worse). What so many of us fail to appreciate is that flu can kill. Having filed a news story, yesterday, on concerns about the potential for development of resistance to the leading flu-fighting drug (Tamiflu), I was sensitized to influenza incidence data. From the World Health Organization...