Arthritis Research

The extent to which vitamin D deficiency may increase susceptibility to a wide range of diseases is dramatically highlighted in newly published research. Scientists have mapped the points at which vitamin D interacts with our DNA -- and identified over two hundred genes that it directly influences.

By enhancing the activity of immune cells that protect against runaway inflammation, researchers at NYU Langone Medical Center may have found a novel therapy for rheumatoid arthritis and other autoimmune diseases.

Wrist fractures have an important personal and public health impact and may play a role in the development of disability in older people, according to a new study published online in the British Medical Journal.

A widely used arthritis drug reduces the incidence of non-melanoma skin cancers -- the most common cancers in humans -- according to a study published this week in the Journal of the National Cancer Institute. The COX-2 inhibitor celecoxib (brand name Celebrex), which is currently approved for the treatment of osteoarthritis, rheumatoid arthritis and acute pain in adults, led to a 62 percent reduction in non-melanoma skin cancers, which includes basal cell carcinomas and squamous cell carcinomas.

Rheumatoid arthritis (RA) sufferers are at an increased risk of dying due to cardiovascular disease. A new five year study published in BioMed Central's...

Women living in the northeastern United States are more likely to develop rheumatoid arthritis (RA), suggesting a link between the autoimmune disease and vitamin D deficiency, says a new study led by a Boston University School of Public Health researcher.

Working to solve the puzzle of when people develop celiac disease has led researchers from the University of Maryland School of Medicine Center for Celiac Research to some surprising findings. They have found that the autoimmune disorder is on the rise with evidence of increasing cases in the elderly. An epidemiological study published September 27 in the Annals of Medicine supports both trends -- with interesting implications for possible treatment and prevention.

In the largest study to date of the Arthritis Foundation's Tai Chi program, participants showed improvement in pain, fatigue, stiffness and sense of well-being. Their ability to reach while maintaining balance also improved, said Leigh Callahan, PhD, the study's lead author, associate professor in the University of North Carolina at Chapel Hill School of Medicine and a member of UNC's Thurston Arthritis Research Center.

Two popular supplements taken by millions of people around the world to combat joint pain, do not work, finds research published online in the British Medical Journal. The supplements, glucosamine and chondroitin, are either taken on their own or in combination to reduce the pain caused by osteoarthritis in hips and knees.

A new study reports that the health-related quality of life (HRQOL) for U.S. adults with arthritis is much worse than for those without this condition. Both physical and mental health are affected by arthritis, which poses a significant health and economic burden as the number of those diagnosed continues to climb. Details of this study are now online in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).