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Free Radicals

Surprise – Free Radicals Shown to Speed Wound Healing

NutritionReview.org - August 13, 2015

Long assumed to be destructive to tissues and cells, "free radicals" generated by the cell's mitochondria – energy-producing structures in the cell – are...

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Researchers Identify New Marker That Predicts Likely Spread of Lung Cancer
Non-small cell lung cancer (NSCLC) is the most commonly diagnosed cancer, and the leading cause of cancer death worldwide. More than half of NSCLC patients die after developing metastases. There are no tests currently that would allow doctors to identify patients where more aggressive therapy could reduce mortality. Researchers at Tulane University have identified a protein on tumor-derived extracellular vesicles that indicates if a NSCLC tumor is likely to metastasize, according to a new study in Science Advances.
Protein in Eye Protects Lens From Damaging Oxidation
The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists from the Technical University of Munich (TUM) has now uncovered the precise structure of the alpha-A-crystallin protein and, in the process, discovered an important additional function.
Study Reveals How Insulin-Like Hormone Relaxin Reverses Cardiovascular Disease
As a healthy heart ages, it becomes more susceptible to cardiovascular diseases. Though researchers have discovered that relaxin, an insulin-like hormone, suppresses atrial fibrillation (AF), inflammation, and fibrosis in aged rats, the underlying mechanisms of these benefits are still unknown. Researchers discuss how relaxin interacts with the body's signaling processes to produce a fundamental mechanism that may have great therapeutic potential.
Keto Diet Works Best in Small Doses in Mouse Study
A ketogenic diet produces health benefits in the short term. As the body burns ketone bodies as an alternative source of fuel, tissue-protective gamma delta T-cells expand throughout the body, but negative effects appear after about a week, researchers found in a study of mice.
Tau Protein Surpasses Amyloid in Predicting Brain Tissue Degeneration of Alzheimer
New research implicates tau protein brain to degeneration in Alzheimer's disease more directly than amyloid, demonstrating potential of tau-based PET (positron emission tomography) brain imaging to improve patient care.
Identification of Key Protein Linked to Senescence, Aging
Aging is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world's population will almost double by 2050. In this context, a new discovery has just broadened scientific knowledge. Researchers shed light on the mechanisms of senescence, by identifying a key protein associated with aging.
Your Brain May Actively Forget During REM Sleep
Rapid eye movement, or REM, sleep is when most of our dreams are made. Now, in a study of mice, a team of Japanese and U.S. researchers show that it may also be a time when the brain actively forgets.
Senescent Cell Burden is Reduced in Humans by Senolytic Drugs
In a small safety and feasibility clinical trial, Mayo Clinic researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed “senolytics”. The result was verified not only in analysis of blood but also in changes in skin and fat tissue senescent cell abundance. The findings appear in the journal EBioMedicine.
Lithium, Trametinib and Rapamycin Combo Extends Lifespan of Fruit Flies by 48%
A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study led by UCL and the Max Planck Institute for Biology of Ageing. The three drugs are all already in use as medical treatments: lithium as a mood stabiliser, trametinib as a cancer treatment and rapamycin as an immune system regulator.
The Scientific Evidence for the Health Benefits of Cordyceps
The Cordyceps fungus is said to have the power to fix a host of health problems, from muscle fatigue to diabetes. But are the claims too good to be true?

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Free Radicals

Surprise – Free Radicals Shown to Speed Wound Healing

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