Inflammation

Many people who are overweight or obese develop insulin resistance and type 2 diabetes at some stage in their lives. A European research team has now discovered that obese people have large amounts of the molecule CXCL5, produced by certain cells in fatty tissue.

The presence of increased body fat, and therefore higher levels of inflammatory substances in the blood, hinders the loss and maintenance of body weight; as shown by a research project of the University of Navarra conducted by Estíbaliz Goyenechea Soto, a scientist at the School of Pharmacy.

A new type of immune cell that can be out of control in certain chronic inflammatory diseases, worsening the symptoms of conditions like psoriasis and asthma, is described for the first time this week in the Journal of Clinical Investigation. The authors of the study, from Imperial College London, the...

More than half of people with chronic cough-a nagging cough that can last for months or even years-suffer from depressive symptoms, according to a study to be presented at the American Thoracic Society International Conference on May 23. The study of 100 people with chronic cough that had lasted an average of 9 years found that...

An overwhelming majority of people who have periodontal (gum) disease are also at high risk for diabetes and should be screened for diabetes, a New York University nursing-dental research team has found. The researchers also determined that half of those at risk had seen a dentist in the previous year, concluded that dentists should consider...

Polyphosphate from blood platelets plays a key role in inflammation and the formation of blood clots, scientists from the Swedish medical university Karolinska Institutet have shown. The study, which is presented in the scientific journal Cell, describes how this mechanism can be used in treatment.

Chemists and biologists from the University of Bath have developed a new technique that could be used to diagnose and develop treatments for age-related conditions like Alzheimer's disease, diabetes and cancer. In these diseases, proteins in the body react with sugars in a process...

Atrial fibrillation (Afib) is the most common type of abnormal heart beat. It is characterized by scarring of the atrial region of the heart (a hallmark known as atrial fibrosis). Although atrial fibrosis is thought to perpetuate Afib, exactly how it develops has not been determined. Some research has suggested...

In a new Mayo Clinic study, researchers found that more than one-third of chronic cough patients given a CT scan had sinusitis, inflammation of the sinuses. Findings will be presented at the American College of Chest Physicians CHEST 2005 meeting in Montreal. "This study suggests that sinusitis is more common than...

Researchers led by Dr. Terrence A. Barrett of Northwestern University Medical School in Chicago. Illinois have discovered that activation of NF-κB, an inflammatory mediator, results in diarrhea in inflammatory bowel disease (IBD). These results are presented in the January 2010 issue of the American Journal of Pathology...

Mango fruit been found to prevent or stop certain colon and breast cancer cells in the lab. That's according to a new study by Texas AgriLife Research food scientists, who examined the five varieties most common in the U.S. Though the mango is an ancient fruit...

Bonn researchers have discovered an elementary mechanism which regulates vital immune functions in healthy people. In situations of hunger which mean stress for the body's cells, the body releases more antimicrobial peptides in order to protect itself. The scientists will publish their results in the journal Nature.