Nutrition Review

Researchers at National Jewish Health have discovered specific molecular and signaling events by which vitamin D inhibits inflammation. In their experiments, they showed that low levels of Vitamin D, comparable to levels found in millions of people, failed to inhibit the inflammatory cascade, while levels considered adequate did inhibit inflammatory signaling. They reported their results in the March 1, 2012, issue of The Journal of Immunology.

Sharks are among the most threatened of marine species worldwide due to unsustainable overfishing. They are primarily killed for their fins to fuel the growing demand for shark fin soup, which is an Asia delicacy. A new study by University of Miami (UM) scientists in the journal Marine Drugs has discovered high concentrations of BMAA in shark fins, a neurotoxin linked to neurodegenerative diseases in humans including Alzheimer's and Lou Gehrig Disease (ALS).

Aspirin works as well as Plavix in patients with blocked leg arteries, a new European study finds. People with the condition, called peripheral artery disease, often suffer from intermittent claudication, which is pain while walking because of decreased blood supply to the legs.

UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases. The receptors are the body's first line of defense against infectious invaders, and they trigger a rush of cytokines, the body's aggressive immune soldiers, into the bloodstream.

Carrying a full load of goods, including 30 tons of ginseng, and finally free of the ice that had choked the harbor for weeks, the Empress of China set out from New York on February 22, 1784 for China. Just months after the British had finally evacuated the city after the Revolutionary War, American merchants were seizing the opportunity afforded by independence to enter the China trade.

In a large analysis of men participating in a prostate drug trial, researchers at the Duke Cancer Institute found a significant correlation between coronary artery disease and prostate cancer, suggesting the two conditions may have shared causes.

Occasional erratic heart rhythms appear to cause about one-fifth of strokes for which a cause is not readily established, according to research presented at the American Stroke Association's International Stroke Conference 2012.About one-third of survivors leave the hospital with the cause of their stroke still undetermined.

A novel bacterium, thought to be a common inhabitant of the oral cavity, has the potential to cause serious disease if it enters the bloodstream, according to a study in the International Journal of Systematic and Evolutionary Microbiology. Its identification will allow scientists to work out how it causes disease and evaluate the risk that it poses.

Sudden cardiac death -catastrophic and unexpected fatal heart stoppage -- is more likely to occur shortly after waking in the morning and in the late night. In a report in the journal Nature, an international consortium of researchers that includes Case Western Reserve University School of Medicine in Cleveland and Baylor College of Medicine explains the molecular linkage between the circadian clock and the deadly heart rhythms that lead to sudden death.

Stress has numerous detrimental effects on the human body. Many of these effects are acutely felt by the sufferer, but many more go 'unseen', one of which is shortening of telomere length. Telomeres are protective caps on the ends of chromosomes and are indicators of aging, as they naturally shorten over time. However, telomeres are also highly susceptible to stress and depression, both of which have repeatedly been linked with premature telomere shortening.