Nutrition Review

Dr. Emil Kozarov and a team of researchers at the Columbia University College of Dental Medicine have identified specific bacteria that may have a key role in vascular pathogenesis, specifically atherosclerosis, or what is commonly referred to as "hardening of the arteries" -- the number one cause of death in the United States.

There is a close relationship between infection outbreaks on teeth and the presence of alopecia areata or localized alopecia, a type of hair loss which has an unknown origin. Alopecia areata starts with bald patches on the scalp, and sometimes elsewhere on the body. The disease occurs in males and females of all ages, and experts believe that it affects 1 out 1000 people.

Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level. In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, MD, chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, has found that stem cells play an unexpected role in explaining what happens in bald scalp.

Swedish researchers present data confirming that that people deprived of sleep for long periods appear less attractive and more unhealthy than those who are well rested. John Axelsson and colleagues conducted an experiment study involving 23 healthy, sleep deprived adults (ages 18 to 31 years) who were photographed and 65 untrained observers (ages 18 to 61 years) who rated the photographs.

The aggregated proteins strewn about the brain are the hallmark of one of the most common neurodegenerative disorders: Alzheimer's disease. But while these irregular, gunky proteins, called amyloid-β, are believed to contribute to the deterioration of memory and cognitive ability in Alzheimer's patients, no one knows how they lead to these symptoms, and the severity of the dementia doesn't directly depend on the amount of amyloid-β plaques found in diseased brains.

Karl Herrup thinks that the national research effort to understand Alzheimer's disease has gone about as far as it can go with its current theories. And that's not far enough. Alzheimer's disease is an incurable, degenerative, eventually fatal disease that attacks cognitive function. It affects more than 26 million people around the world and is the most common form of dementia among people over the age of 65.

Walking may slow cognitive decline in adults with mild cognitive impairment (MCI) and Alzheimer's disease, as well as in healthy adults, according to a study presented November 29 at the annual meeting of the Radiological Society of North America (RSNA).

The global effort to outlaw herbs, vitamins and supplements is well under way, and in just four months, hundreds of herbal products will be criminalized in the UK and across the EU. It's all part of an EU directive passed in 2004 which erects "disproportionate" barriers against herbal remedies by requiring them to be "licensed" before they can be sold.

Another example of commensal microbes that affect host immunity may hold implications for the treatment of autoimmune diseases and other ailments. An abundant type of bacteria that resides in the intestines is critical for keeping the immune system of the colon in check, according to a study published online today (December 23) in ScienceExpress.

By tweaking a single gene, scientists have mimicked in sedentary mice the heart-strengthening effects of two weeks of endurance training, according to a report from Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center (BIDMC). The genetic manipulation spurred the animals' heart muscle cells -- called cardiomyocytes -- to proliferate and grow larger by an amount comparable to normal mice that swam for up to three hours a day, the authors write in the journal Cell.