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Nicotinomide Riboside Mimics Caloric Restriction, May Reverse Cardiovascular Aging

NutritionReview.org - April 2, 2018

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Scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combating antimicrobial resistance (AMR).
Synthetic Llama Antibodies Rescue Doomed Proteins Inside Cells
Researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells. The approach could be used to treat dozens of diseases, including cystic fibrosis, that arise from the destruction of imperfect but still perfectly functional proteins.
Scientists Reverse Age-Related Vision Loss, Eye Damage From Glaucoma in Mice
Researchers at Harvard Medical School have successfully reversed age-related vision loss in animals as well as eye damage stemming from with a condition mimicking human glaucoma, a leading cause of blindness around the world.
Cervical Cancer Survival May Improve by Targeting Senescent Cells
How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a 'zombie' cell state called senescence, scientists report.
Researchers Discover New Particle in Blood of Septic Patients
Researchers have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.
Quercetin Activates Proteins Important for Human Brain and Heart Health
Quercetin, a plant-derived bioflavonoid compound commonly found in pickled capers, has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.
Multivitamin, Mineral Supplement Linked to Less-Severe, Shorter-Lasting Illness Symptoms
Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitamin C in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo.
Cashew Shell Compound Appears to Mend Damaged Nerves
In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports in the Proceedings of the National Academy of Sciences.
Eosinophil Cell Therapy Reverses Age-Related Impairments, Promotes Rejuvenation
Researchers demonstrate in an animal model that age-related frailty and immune decline can be halted and even partially reversed using a novel cell-based therapeutic approach.
Tocilizumab Calms 'Cytokine Storm' to Reduce Risk of Dying by 45 Percent in COVID-19 Patients on Ventilators
Patients who received single intravenous dose of tocilizumab were also more likely to leave the hospital or be off ventilator within a month, despite double the risk of additional infection, according to a new study.

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Nicotinomide Riboside Mimics Caloric Restriction, May Reverse Cardiovascular Aging

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