It seems that while the practice of bloodletting throughout history had little or no effect on most diseases, and the practice was abandoned in the 19th century, new research published in BioMed Central’s open access journal BMC Medicine demonstrates that blood donation has real benefits for obese people with metabolic syndrome. Two sessions of bloodletting were enough to improve blood pressure and markers of cardiovascular disease.
The iron-reduction patients had 300ml of blood removed at the start of the trial and between 250 and 500ml removed four weeks later. Six weeks later, allowing plenty of time for blood volume to be replaced, the patients who gave blood had a significant reduction in systolic blood pressure (from 148 mmHg to 130 mmHg) as well as reduction in blood glucose levels and heart rate, and an improvement in cholesterol levels (LDL/HDL ratio).
Prof Andreas Michalsen from the Charité-University Medical Centre, Berlin, who led this research explained, “Consecutive reduction in iron stores was able to improve markers of cardiovascular risk and glycemic control. Consequently blood donation may prevent not just diabetes but also cardiovascular disease for the obese. Obviously this treatment will not be suitable for people with anemia however for those eligible for treatment blood donation may prevent escalation of their condition.”
- Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Bröcker-Preuss, Thomas Rampp, Benno Brinkhaus and Andreas Michalsen. Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: Results from a randomized clinical trial. BMC Medicine, 2012 [link]