GABA (gamma aminobutyric acid), is an important amino acid which functions as the most prevalent inhibitory neurotransmitter in the central nervous system. Supplemental GABA can be useful in producing a state of relaxation. GABA works in partnership with a derivative of Vitamin B-6, pyridoxine, to cross from the axons to the dendrites through the synaptic cleft, in response to an electrical signal in the neuron and inhibits message transmission. This helps control the nerve cells from firing too fast, which would overload the system.
The action of GABA decreases epileptic seizures and muscle spasms by inhibiting electrical signals in this manner. Studies have shown that the site of action in the brain of benzodiazepams, including Valium, is directly coupled to the brain receptor for GABA. GABA itself can be taken instead of a tranquilizer to calm the body without the fear of addiction. Taken with the B-vitamins niacinamide and inositol, it prevents anxiety messages from reaching the motor centers of the brain by filling its receptor site.