Life Extension

Scientists have recently succeeded in rejuvenating cells from elderly donors (aged over 100). These old cells were reprogrammed in vitro to induced pluripotent stem cells (iPSC) and to rejuvenated and human embryonic stem cells (hESC): cells of all types can again be differentiated after this genuine "rejuvenation" therapy

When the body fights oxidative damage, it calls up a reservist enzyme that protects cells -- but only if those cells are relatively young, a study has found. Biologists at USC discovered major declines in the availability of an enzyme, known as the Lon protease, as human cells grow older.

Researchers at the Johns Hopkins University School of Medicine have found a protein normally involved in blood pressure regulation in a surprising place: tucked...

Researchers have discovered a new mechanism controlling aging in white blood cells. The research, published in the September issue of the Journal of Immunology,...

The neurotransmitter dopamine is best known for its roles in the brain -- in signaling pathways that control movement, motivation, reward, learning and memory. Now, Vanderbilt University Medical Center investigators have demonstrated that dopamine produced outside the brain -- in the kidneys -- is important for renal function, blood pressure regulation and life span.

Lack of physical exercise is often implicated in many disease processes. However, sedentary behavior, or too much sitting, as distinct from too little exercise, potentially could be a new risk factor for disease. The August issue of the American Journal of Preventive Medicine features a collection of articles that addresses many aspects of the problem of sedentary behavior...

Excess nutrients, such as fat and sugar, don't just pack on the pounds but can push some cells in the body over...

Self-conscious about your age? Careful where you spit. UCLA geneticists now can use saliva to reveal how old you are. The June 22 advance online edition of the Public Library of Science (PLoS) ONE publishes the findings, which offer a myriad of potential applications. A newly patented test based on the research, for example, could offer crime-scene investigators a new forensic tool for pinpointing a suspect's age.

A group of volunteers ate half a kilo of strawberries every day for two weeks to demonstrate that eating this fruit improves the antioxidant capacity of blood. The study, carried out by Italian and Spanish researchers, showed that strawberries boost red blood cells' response to oxidative stress, an imbalance that is associated with various diseases.

A University of Florida review of research finds the polyphenol compound known as resveratrol found in red wine, grapes and other fruits may not prevent old age, but it might make it more tolerable. News stories have long touted resveratrol as a cure for various diseases and a preventative against aging.

IHME researchers, in collaboration with researchers at Imperial College London, found that between 2000 and 2007, more than 80% of counties fell in standing against the average of the 10 nations with the best life expectancies in the world, known as the international frontier.

A decline in testosterone levels as men grow older is likely the result -- not the cause -- of deteriorating general health, say...