Life Extension

By Ward Dean, MD Every cell in the human body is packed with tiny organelles called mitochondria (Fig. 1). Mitochondria are often referred to as...

In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study in the June 5 issue...

The accumulation of misfolded protein marks the accrual of years as the body ages. Could heat shock proteins be used to reduce the effects of aging and diminish the risk of disease by untangling improperly folded proteins?

As long as humans have been alive, they've been seeking ways to extend life just a little longer. So far no one has found...

A major new study claims the pricey supplement TA-65 may turn back the clock, all the way down to our DNA—but many scientists are brushing it off as snake oil. Thea Singer investigates. In an era of seemingly magical technology, the notion that scientists could develop a pill that might slow the aging process doesn’t seem that far-fetched.

When the body fights oxidative damage, it calls up a reservist enzyme that protects cells -- but only if those cells are relatively young, a study has found. Biologists at USC discovered major declines in the availability of an enzyme, known as the Lon protease, as human cells grow older.

Glucosamine has been freely available in drugstores for many decades. It is widely used to treat arthritis and to prevent joint degeneration. Moreover, glucosamine...

Alarming new data published today by the International Osteoporosis Foundation (IOF), shows that one-third of all hip fractures worldwide occur in men, with mortality...

Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer's, and diabetes. But according to a Yale School of...

If you think life's too short, then you're not alone. A team of scientists set out to find what it would take to live a very long life and they made important discoveries that bring longer life spans much closer to reality. A new research report featured on the cover of The FASEB Journal, describes how scientists "activated" life extension in the roundworm C. elegans, and in the process discovered a new metabolic state correlating with long life.

Biologists have identified a gene that can slow the aging process when activated remotely in key organ systems. The life scientists, working with fruit...

The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. Researchers...