Friday, September 25, 2020

Use Of Low Dose Aspirin To Protect Against Cardiovascular Disease Should...

The latest issue of the Drug and Therapeutics Bulletin (DTB) reports that the use of low-dose aspirin to protect against heart attacks and strokes in individuals yet to develop obvious cardiovascular disease, should be abandoned. Low-dose aspirin is widely used to prevent further episodes of cardiovascular disease in people who have already had problems such as a heart attack or stroke. This approach is known as secondary prevention. It is well established and of confirmed benefit....

Promise Of A New Lupus Treatment Is A Groundbreaking Achievement

Human Genome Sciences (HGS) and GlaxoSmithKline (GSK) today announced positive results from BLISS-76, the second of two large-scale phase III clinical trials of BENLYSTA™ (belimumab) for treating systemic lupus. A full presentation of results from BLISS-52 was recently shared at the 73rd Annual Scientific meeting of the American College of Rheumatology. Both trials succeeded in meeting their primary endpoints, which...

Biochemical Signals Associated With Atherosclerosis May Damage Other Organs

Many scientists view atherosclerosis, or hardening of the arteries, as a localized disease characterized by the build up of fatty plaques in the arteries, which can eventually cause heart attacks and strokes. Now, in a finding that challenges conventional knowledge, researchers in New York and North Carolina report that plaques formed in arteries are...

New Thrombosis Treatments? Blood Clots Form Through Newly Discovered Mechanism

Polyphosphate from blood platelets plays a key role in inflammation and the formation of blood clots, scientists from the Swedish medical university Karolinska Institutet have shown. The study, which is presented in the scientific journal Cell, describes how this mechanism can be used in treatment.

Aerobic Exercise No Big Stretch For Older Adults But Helps Elasticity...

Just three months of physical activity reaps heart health benefits for older adults with type 2 diabetes by improving the elasticity in their arteries -- reducing risk of heart disease and stroke, Dr. Kenneth Madden told the 2009 Canadian Cardiovascular Congress, co-hosted by the Heart and Stroke Foundation and the...

New Stroke Therapy Successful in Rats: Protein Completely Restores Motor Function

People with impaired mobility after a stroke soon may have a therapy that restores limb function long after the injury, if a supplemental protein works as well in humans as it does. Two new studies by UC Irvine biologists have found that a protein naturally occurring in humans restores...

How One Form of Natural Vitamin E Protects Brain After Stroke

Blocking the function of an enzyme in the brain with a specific kind of vitamin E can prevent nerve cells from dying after a stroke, new research suggests. In a study using mouse brain cells, scientists found that the tocotrienol form of vitamin E, an alternative to the popular drugstore supplement, stopped the enzyme from...

Blood Glucose And Risk Of Incident And Fatal Cancer In The...

Tanja Stocks and colleagues carry out an analysis of six European cohorts and confirm that abnormal glucose metabolism is linked with increased risk of cancer overall and at specific sites.

Sugary Soft Drinks Linked To Increased Risk Of Gout In Men

Consumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men, finds a study published by the British Medical Journal. Gout is a joint disease which causes extreme pain and swelling. It is most common in...

Too Much Sugar Is Bad, But Which Sugar Is Worse: Fructose...

In 2005, the average American consumed 64kg of added sugar, a sizeable proportion of which came through drinking soft drinks. Now, in a 10-week study, Peter Havel and colleagues, at the University of California at Davis, Davis, have provided evidence that human consumption of...

Molecular ‘Firing Squad’ In Mice Triggered By Overeating Destroys Metabolism

Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes. The new study...

Dietary Formula That Maintains Youthful Function Into Old Age

Researchers at McMaster University have developed a cocktail of ingredients that forestalls major aspects of the aging process. The findings are published in the...