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Halting Cell Recycling (Autophagy) to Treat Cancer
Targeting and changing autophagy, otherwise known as cell recycling, has been linked to helping control or diminish certain cancers. Now, researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day.
Animal and Human Data Reveal New Target for Reversing Age-Related Decline
A new study shows that humans express a powerful hormone during exercise and that treating mice with the hormone improves physical performance, capacity and fitness. Researchers say the findings present new possibilities for addressing age-related physical decline.
Compound Slows Bone Loss and Extends Lifespan in Animal Studies, May Aid in Treatments to Slow Aging
Benzoxazole, the compound that slowed bone aging by up to 31% over the course of a year's treatment in the mice, was first identified as one of five compounds that extended nematode lifespan in the Lithgow lab in a study that appeared in Nature in 2011.
New Class of Antibiotics Kill a Wide Range of Antibiotic-Resistant Bacteria
Scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combating antimicrobial resistance (AMR).
Synthetic Llama Antibodies Rescue Doomed Proteins Inside Cells
Researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells. The approach could be used to treat dozens of diseases, including cystic fibrosis, that arise from the destruction of imperfect but still perfectly functional proteins.
Scientists Reverse Age-Related Vision Loss, Eye Damage From Glaucoma in Mice
Researchers at Harvard Medical School have successfully reversed age-related vision loss in animals as well as eye damage stemming from with a condition mimicking human glaucoma, a leading cause of blindness around the world.
Cervical Cancer Survival May Improve by Targeting Senescent Cells
How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a 'zombie' cell state called senescence, scientists report.
Researchers Discover New Particle in Blood of Septic Patients
Researchers have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.
Quercetin Activates Proteins Important for Human Brain and Heart Health
Quercetin, a plant-derived bioflavonoid compound commonly found in pickled capers, has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.
Multivitamin, Mineral Supplement Linked to Less-Severe, Shorter-Lasting Illness Symptoms
Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitamin C in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo.

Deep Sleep Aids Brain Waste Removal to Prevent Neurodegenerative Diseases

New ‘Skeletal Age’ Calculator Predicts Risk of Bone Fracture, Premature Death

Parasitic Hookworms May Help Humans Live Longer Lives Free of Chronic…

NSAIDs Pain Relievers Like Acetaminophen and Ibuprofen May Blunt Effectiveness of…

Preserving Vision and Preventing Degenerative Disorders

Gastric Balance: Heartburn Not Always Caused by Excess Acid

Restoring Bladder Control to Prevent Incontinence

Of Brains and Bones: How Hunger Neurons Control Bone Mass

Gum Health Linked to Heart Disease, Diabetes, Rheumatoid Arthritis and Prostate…

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