Diabetes Research

University of Cincinnati (UC) researchers have determined why a certain class of diabetes drugs leads to weight gain and have found that the molecular system involved (PPAR-γ found in the brain) is also triggered by consumption of high-fat foods.

New research uncovers a molecular mechanism that links diabetes with an increased risk of cardiovascular problems and sudden cardiac death. The study, published by Cell Press in the June 24 issue of the journal Neuron, finds that high blood sugar prevents vital communication between the brain and the autonomic nervous system,

Osteoporosis is more common in women who have fractured bones when they were younger -- and they experience a similar loss in health-related quality of life as those with arthritis, lung disease, diabetes and other chronic diseases.

Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also showed, for the first time, how a loss in homeostasis in this group of T cells most likely promotes chronic inflammation associated with T2D.

More young people and adults in their 30s and 40s are being hospitalized for stroke, even as stroke rates are dropping in older people, new data show. The findings, reported this week at the American Stroke Association conference in Dallas, may be a sign that that rising rates of obesity, diabetes and high blood pressure among teenagers and young adults are taking a toll. Or it may simply be that physicians have improved their diagnosis and reporting of stroke in young people during the past decade.

Garlic has "significant" potential for preventing cardiomyopathy, a form of heart disease that is a leading cause of death in people with diabetes, scientists...

A study recently published in Nature Genetics has found new evidence for a link between the body clock hormone melatonin and type 2 diabetes. The study found that people who carry rare genetic mutations in the receptor for melatonin have a much higher risk of type 2 diabetes.

United States and Japanese researchers have identified a key step in metabolic pathways linked to diabetes and cancer. The study on activation...

An inexpensive drug that treats Type-2 diabetes has been shown to prevent a number of natural and human-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State University researcher.

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that individuals with fatty liver were five times more likely to develop type 2 diabetes than those without fatty liver. This higher risk seemed to occur regardless of the patient's fasting insulin levels, which were used as a marker of insulin resistance.

Researchers at the Johns Hopkins University School of Medicine have found a protein normally involved in blood pressure regulation in a surprising place: tucked...

UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases. The receptors are the body's first line of defense against infectious invaders, and they trigger a rush of cytokines, the body's aggressive immune soldiers, into the bloodstream.