Thursday, February 2, 2023

Intensive-Dose Statin Therapy Associated With Increased Risk Of Diabetes

An analysis of data from previously published studies indicates that intensive-dose statin therapy is associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a study in the June 22/29 issue of JAMA.

Bone-Cell Control Of Energy Generation Is Regulated By The Protein Atf4

Bone cells known as osteoblasts were recently shown to have a role in controlling the biochemical reactions that generate energy via secretion of the molecule osteocalcin. Gerard Karsenty and colleagues, at Columbia University College of Physicians and Surgeons, New York, therefore hypothesized that osteoblasts express a regulatory gene(s) that controls this osteoblast function and then identified Atf4 as this regulatory gene in mice.

Why Coffee Drinking Reduces The Risk Of Type 2 Diabetes

Why do heavy coffee drinkers have a lower risk of developing Type 2 diabetes, a disease on the increase around the world that can lead to serious health problems? Scientists are offering a new solution to that long-standing mystery in a report in ACS' Journal of Agricultural & Food Chemistry.

Common Test Could Help Predict Early Death In Diabetes, Study Shows

New findings out of Wake Forest Baptist Medical Center reveal that a common test may be useful in predicting early death in individuals with diabetes. The study appears in the May issue of Diabetes Care.

Research Offers Insight To How Fructose Causes Obesity And Other Illness

A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes. In this study which was performed in lab animals, researchers found that fructose can be metabolized by an enzyme that exists in two forms.

Bone Control of Glucose Levels

Bone cells known as osteoblasts were recently shown to have a role in controlling the biochemical reactions that generate energy via secretion of the molecule osteocalcin. A team of researchers, led by Stavroula Kousteni, at Columbia University, New York, has now determined that the protein FoxO1 regulates this function of osteoblasts in mice.

New Link Found Between Obesity And Insulin Resistance

Obesity is the main culprit in the worldwide avalanche of Type 2 diabetes. But how excess weight drives insulin resistance, the condition that may lead to the disease, is only partly understood. Scientists at Joslin Diabetes Center now have uncovered a new way in which obesity wreaks its havoc, by altering the production of proteins that affect how other proteins are spliced together.

Right Food Effectively Protects Against Risk For Diabetes, Cardiovascular Disease And...

For the first time, researchers in Sweden have found out what effect multiple, rather than just single, foods with anti-inflammatory effects have on healthy individuals. The results of a diet study show that bad cholesterol was reduced by 33 per cent, blood lipids by 14 per cent, blood pressure by 8 per cent and a risk marker for blood clots by 26 per cent. A marker of inflammation in the body was also greatly reduced, while memory and cognitive function were improved.

‘Master Switch’ Gene For Obesity And Diabetes Discovered

A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour of other genes found within fat in the body.

Diabetes Drug Side Effects Traced To Fat Action

For better or worse, a popular class of anti-diabetic drugs does more than lower blood sugar. One known as rosiglitazone (trade name Avandia) has been in the spotlight for its possible link to increased cardiovascular events, but it also seems to come with unexplained vascular benefits and an unwelcome tendency for weight gain.